You don’t always have to double click on icons, files, and folders to open them. You can customize your mouseclick to suit your needs. I personally like to dispose of the double clicking and choose single click with underlining. So when you move your mouse over a filename or folder it will become underlined and makes it very clear that you are about to click on it.

How to change mouse clicking from double click to single click in Windows Vista.

1. Go to the start menu and choose computer
2. From the menu, choose tools. If there is no menu you can press the ALT key for them to appear. Also see Show the old menu with file, edit, tools, and view in Windows Vista.
3. Then choose Folder Options from the menu.
4. On the general tab undering the heading click items as follows, choose single-click to open an item.
5. Then choose which single click option you want to use.
6. Then press apply and ok.

 Watch this video tutorial to see an example of the different types of single click options in Windows Vista.